Hewlett Packard Enterprise P49653-B21 - 2 GHz Processor with 16 Cores - Gray

Hewlett Packard Enterprise P49653-B21 brings enterprise-grade performance with an Intel Xeon Scalable 4th Gen 5416S processor running at a 2 GHz base frequency, delivering a powerful balance of throughput and efficiency.

This Intel® Xeon® Gold 5416S CPU features 16 physical cores and 32 threads, a 30 MB L3 cache and a 150 W TDP, making it ideal for sustained datacenter workloads and virtualized environments. It supports octa-channel DDR5 memory at up to 4400 MHz and can address up to 4 TB of RAM, ensuring high memory bandwidth for large-scale applications.

The processor offers advanced performance technologies including Intel® Turbo Boost 2.0 up to 4 GHz, Intel® Hyper-Threading, and a mix of high-priority and low-priority cores (4 high-priority cores at 2.1 GHz and 12 low-priority cores at 1.7 GHz) to optimize mixed workloads and power efficiency.

Security and platform resilience are built in, with Intel® AES-NI, Intel® Trusted Execution Technology, Intel® Total Memory Encryption, Intel® Control-flow Enforcement Technology (CET), Intel® Boot Guard, and Intel® Platform Firmware Resilience Support. These features help protect sensitive data and maintain platform integrity in multi-tenant and regulated environments.

Virtualization and acceleration capabilities are extensive: Intel VT-x, VT-d, Extended Page Tables (EPT), Intel® QuickAssist Technology (QAT), QuickAssist Software Acceleration, Dynamic Load Balancer (DLB), Data Streaming Accelerator (DSA) and Intel® Deep Learning Boost are supported, enabling efficient virtualization, cryptographic offload and AI inference acceleration.

With support for advanced instruction sets (AMX, AVX, AVX2, AVX-512, SSE4.2) and features such as Intel® Speed Select (SST-PP, SST-BF), Resource Director Technology (RDT) and Run Sure Technology, this processor is tuned for performance-sensitive, latency-critical and throughput-heavy server tasks.

The P49653-B21 is designed without integrated or discrete graphics, focusing on CPU-centric compute. Its compact dimensions (36.6 mm width, 222.3 mm depth, 287.3 mm height) and 680 g weight make it straightforward to integrate into server modules and blade systems that accept LGA 4677 (Socket E).

Use cases include virtualized cloud hosts, database and analytics servers, AI inference nodes, cryptographic gateways and high-performance computing clusters. Key selling points are its 16 cores/32 threads, 4 GHz boost, DDR5 octa-channel memory support up to 4 TB, comprehensive security features, and built-in acceleration for cryptography and AI.

• 16 cores / 32 threads (Intel® Xeon® Gold 5416S)
• 2 GHz base, up to 4 GHz turbo, 30 MB L3 cache
• Octa-channel DDR5 up to 4400 MHz, supports 4 TB
• Comprehensive security and virtualization features
• Hardware accelerators: QAT (2), DLB (2), DSA (1)